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Article

Association of the 5,10-methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) polymorphisms in Korean patients with adult acute lymphoblastic leukemia.

Anticancer research - 1 Jan 2000

Oh Doyeun, Kim Nam Keun, Jang Moon Ju, Kim Hugh Chul, Lee Jae Hoon, Lee Jung Ae, Ahn Myung Ju, Kim Chul Soo, Kim Heung Sik, Park Seonyang, Chio Hyun Sook, Min Yoo Hong

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) plays a central role in converting folate to methyl donor for DNA methylation. Because MTHFR is a key enzyme in folate metabolism, changes in its activity resulting from polymorphisms in the MTHFR gene could modify the susceptibility to canc...

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Source

Identifiers

PMID: 17970089

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17970089-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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