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Article

Association analysis of the catechol-O-methyltransferase /methylenetetrahydrofolate reductase genes and cognition in late-onset depression.

Psychiatry and clinical neurosciences - 1 May 2014

Wang Xiaoquan, Wang Zusen, Wu Yanfeng, Yuan Yonggui, Hou Zhenghua, Hou Gang

Abstract excerpt

AIMS: Increasing evidence suggests that the catechol-O-methyltransferase (COMT) gene might be associated with cognition in patients with mental disorders and healthy people. The metabolic pathways of COMT and methylenetetrahydrofolate reductase (MTHFR) are closely interconnected. In this study, w...

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Source

Identifiers

PMID: 24373005
DOI: 10.1111/pcn.12133

Genes

COMT
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24373005-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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