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Article

The enzymatic activities of brain catechol-O-methyltransferase (COMT) and methionine sulphoxide reductase are correlated in a COMT Val/Met allele-dependent fashion.

Neuropathology and applied neurobiology - 1 Dec 2015

Moskovitz Jackob, Walss-Bass Consuelo, Cruz Dianne A, Thompson Peter M, Hairston Jenaqua, Bortolato Marco

Abstract excerpt

AIMS: The enzyme catechol-O-methyltransferase (COMT) plays a primary role in the metabolism of catecholamine neurotransmitters and is implicated in the modulation of cognitive and emotional responses. The best characterized single nucleotide polymorphism (SNP) of the COMT gene consists of a valin...

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Identifiers

PMID: 25640985
DOI: 10.1111/nan.12219
PMCID: PMC4500745

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25640985-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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