Article
Genetic mutation screen in early non--small-cell lung cancer (NSCLC) specimens.
Clinical lung cancer - 1 Mar 2014
Bar Jair, Damianovich Maya, Hout Siloni Goni, Dar Erel, Cohen Yoram, Perelman Marina, Ben Nun Alon, Simansky David, Yellin Alon, Urban Damien, Onn Amir
Abstract excerpt
BACKGROUND: Testing for genetic abnormalities in epithelial growth factor receptor (EGFR), anaplastic lymphoma receptor tyrosine kinase (ALK), and potentially additional genes is a critical tool in the care of advanced NSCLC. There is conflicting evidence for the role of such tests in early NSCLC. We report a single-institute Sequenom testing for a wide range of mutations and their clinical correlations in...
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