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Article

Common and rare EGFR and KRAS mutations in a Dutch non-small-cell lung cancer population and their clinical outcome.

PloS one - 1 Jan 2013

Kerner Gerald S M A, Schuuring Ed, Sietsma Johanna, Hiltermann Thijo J N, Pieterman Remge M, de Leede Gerard P J, van Putten John W G, Liesker Jeroen, Renkema Tineke E J, van Hengel Peter, Platteel Inge, Timens Wim, Groen Harry J M

Abstract excerpt

INTRODUCTION: In randomly assigned studies with EGFR TKI only a minor proportion of patients with NSCLC have genetically profiled biopsies. Guidelines provide evidence to perform EGFR and KRAS mutation analysis in non-squamous NSCLC. We explored tumor biopsy quality offered for mutation testing,...

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Identifiers

PMID: 23922984
DOI: 10.1371/journal.pone.0070346
PMCID: PMC3726644

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23922984-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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