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Article

Genetic and epigenetic analysis of erbB signaling pathway genes in lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Dec 2010

Hoque Mohammad Obaidul, Brait Mariana, Rosenbaum Eli, Poeta Maria Luana, Pal Prodipto, Begum Shahnaz, Dasgupta Santanu, Carvalho Andre L, Ahrendt Steven A, Westra William H, Sidransky David

Abstract excerpt

BACKGROUND: Prognosis for patients with non-small cell lung cancer (NSCLC) is poor. The potential value of modulating epidermal growth factor receptor (EGFR) for treatment is reflected by the recent approval of specific drugs that inhibit its activity. Mutations in EGFR were reported in lung canc...

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Source

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Identifiers

PMID: 21102258
DOI: 10.1097/JTO.0b013e3181f77a53
PMCID: PMC3057519

Genes

EGFR
BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21102258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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