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Article

Biological role of prolyl 3-hydroxylation in type IV collagen.

Proceedings of the National Academy of Sciences of the United States of America - 7 Jan 2014

Pokidysheva Elena, Boudko Sergei, Vranka Janice, Zientek Keith, Maddox Kerry, Moser Markus, Fässler Reinhard, Ware Jerry, Bächinger Hans Peter

Abstract excerpt

Collagens constitute nearly 30% of all proteins in our body. Type IV collagen is a major and crucial component of basement membranes. Collagen chains undergo several posttranslational modifications that are indispensable for proper collagen function. One of these modifications, prolyl 3-hydroxylation, is accomplished by a family of prolyl 3-hydroxylases (P3H1, P3H2, and P3H3). The present study shows that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24368846
DOI: 10.1073/pnas.1307597111
PMCID: PMC3890855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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