Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development

4 Mar 1997

Abstract excerpt

Type III collagen is a fibrillar forming collagen comprising three alpha1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. Mutations in the COL3A1 gene have been implicated as a cause of type IV Ehlers-Danlos syndrome, a disease leading to aortic rupture in early...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Connective tissue disorders research
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9050868
DOI: 10.1073/pnas.94.5.1852

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular developmentPMID 9050868Read ↗

Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model.Semantic proximity Read ↗

Haploinsufficiency of the murine Col3a1 locus causes aortic dissection: a novel model of the vascular type of Ehlers-Danlos syndrome.Semantic proximity Read ↗

The haploinsufficient Col3a1 mouse as a model for vascular Ehlers-Danlos syndrome.Semantic proximity Read ↗

Comparative therapeutic strategies for preventing aortic rupture in a mouse model of vascular Ehlers Danlos syndromeSemantic proximity Read ↗

Generation of two iPSC lines from vascular Ehlers-Danlos Syndrome (vEDS) patients carrying a missense mutation in COL3A1 geneSemantic proximity Read ↗

Ehlers-Danlos syndrome type IV is associated with a novel G984R COL3A1 mutation.Semantic proximity Read ↗

Angiotensin II promotes thoracic aortic dissections and ruptures in Col3a1 haploinsufficient mice.Semantic proximity Read ↗

Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations provides molecular insights into the etiopathology of vascular Ehlers-Danlos syndrome.Semantic proximity Read ↗

Elastic and collagenous networks in vascular diseases.Semantic proximity Read ↗

A novel mutation in COL3A1 associates to vascular Ehlers-Danlos syndrome with predominant musculoskeletal involvement.Semantic proximity Read ↗

Haploinsufficiency for one COL3A1 allele of type III procollagen results in a phenotype similar to the vascular form of Ehlers-Danlos syndrome, Ehlers-Danlos syndrome type IV.Semantic proximity Read ↗

Aortic Tissue Proteome Alterations in Vascular Ehlers-Danlos Syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.