Article
Molecular characterization of clonal interference during adaptive evolution in asexual populations of Saccharomyces cerevisiae.
Nature genetics - 1 Dec 2008
Kao Katy C, Sherlock Gavin
Abstract excerpt
The classical model of adaptive evolution in an asexual population postulates that each adaptive clone is derived from the one preceding it. However, experimental evidence has suggested more complex dynamics, with theory predicting the fixation probability of a beneficial mutation as dependent on...
Topics
- Directed Molecular Evolution
- Gene Expression Profiling
- Mutation
- Oligonucleotide Array Sequence Analysis
- Saccharomyces cerevisiae
