Molecular characterization of clonal interference during adaptive evolution in asexual populations of Saccharomyces cerevisiae.

Abstract excerpt

The classical model of adaptive evolution in an asexual population postulates that each adaptive clone is derived from the one preceding it. However, experimental evidence has suggested more complex dynamics, with theory predicting the fixation probability of a beneficial mutation as dependent on the mutation rate, population size and the mutation's selection coefficient. Clonal interference has been demonstrated...

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