Article
Standing genetic variation drives repeatable experimental evolution in outcrossing populations of Saccharomyces cerevisiae.
Molecular biology and evolution - 1 Dec 2014
Burke Molly K, Liti Gianni, Long Anthony D
Abstract excerpt
In "evolve-and-resequence" (E&R) experiments, whole-genome sequence data from laboratory-evolved populations can potentially uncover mechanisms of adaptive change. E&R experiments with initially isogenic, asexually reproducing microbes have repeatedly shown that beneficial de novo mutations drive adaptation, and these mutations are not shared among independently evolving replicate populations. Recent E&R...
Topics
- Base Sequence
- Directed Molecular Evolution
- Evolution, Molecular
- Gene Frequency
- Genes, Fungal
- Haplotypes
- Models, Genetic
- Polymorphism, Single Nucleotide
- Saccharomyces cerevisiae