Article
Praziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infections.
PLoS neglected tropical diseases - 1 Jan 2013
Coeli Regina, Baba Elio H, Araujo Neusa, Coelho Paulo M Z, Oliveira Guilherme
Abstract excerpt
BACKGROUND: Schistosomiasis has a considerable impact on public health in many tropical and subtropical areas. In the new world, schistosomiasis is caused by the digenetic trematode Schistosoma mansoni. Chemotherapy is the main measure for controlling schistosomiasis, and the current drug of choice for treatment is praziquantel (PZQ). Although PZQ is efficient and safe, its repetitive large-scale use in endemic...
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