Article
Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda.
Parasites & vectors - 27 Dec 2019
Faust Christina L, Crotti Marco, Moses Arinaitwe, Oguttu David, Wamboko Aidah, Adriko Moses, Adekanle Elizabeth K, Kabatereine Narcis, Tukahebwa Edridah M, Norton Alice J, Gower Charlotte M, Webster Joanne P, Lamberton Poppy H L
Abstract excerpt
BACKGROUND: A key component of schistosomiasis control is mass drug administration with praziquantel. While control interventions have been successful in several endemic regions, mass drug administration has been less effective in others. Here we focus on the impact of repeated praziquantel treatment on the population structure and genetic diversity of Schistosoma mansoni. METHODS: We examined S. mansoni...
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