Article
Regular treatments of praziquantel do not impact on the genetic make-up of Schistosoma mansoni in Northern Senegal.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2013
Huyse T, Van den Broeck F, Jombart T, Webster B L, Diaw O, Volckaert F A M, Balloux F, Rollinson D, Polman K
Abstract excerpt
The Senegal River Basin (SRB) experienced a major epidemic of intestinal schistosomiasis in the early nineties, after the construction of a dam for irrigation purposes. Exceptionally low cure rates following praziquantel (PZQ) treatment at the onset of the epidemic raised concerns about PZQ resis...
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