Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme.

Parasites & vectors - 2 Dec 2017

Gower Charlotte M, Gehre Florian, Marques Sara R, Lamberton Poppy H L, Lwambo Nicholas J, Webster Joanne P

Abstract excerpt

BACKGROUND: Schistosoma mansoni is a parasite of profound medical importance. Current control focusses on mass praziquantel (PZQ) treatment of populations in endemic areas, termed Preventative Chemotherapy (PC). Large-scale PC programmes exert prolonged selection pressures on parasites with the potential for, direct and/or indirect, emergence of drug resistance. Molecular methods can help monitor genetic changes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthelmintics
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Genetic Variation

Share to National Health Programs

Share to Schistosoma mansoni

Share to Schistosomiasis mansoni

Share to Tanzania

Source

Open in PubMed Open full text

Identifiers

PMID: 29197426
DOI: 10.1186/s13071-017-2533-6
PMCID: PMC5712074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic and genotypic monitoring of Schistosoma mansoni in Tanzanian schoolchildren five years into a preventative chemotherapy national control programme.PMID 29197426Read ↗

Genetic consequences of mass human chemotherapy for Schistosoma mansoni: population structure pre- and post-praziquantel treatment in Tanzania.Semantic proximity Read ↗

Two-year longitudinal survey reveals high genetic diversity of Schistosoma mansoni with adult worms surviving praziquantel treatment at the start of mass drug administration in Uganda.Semantic proximity Read ↗

No apparent reduction in schistosome burden or genetic diversity following four years of school-based mass drug administration in mwea, central kenya, a heavy transmission area.Semantic proximity Read ↗

Praziquantel treatment decreases Schistosoma mansoni genetic diversity in experimental infections.Semantic proximity Read ↗

Potential drivers for schistosomiasis persistence: population genetic analyses from a cluster-randomized urogenital schistosomiasis elimination trial across the Zanzibar islandsSemantic proximity Read ↗

Evidence for Reduced Malaria Parasite Population after Application of Population-Level Antimalarial Drug Strategies in Southern Province, Zambia.Semantic proximity Read ↗

Population genetics of Schistosoma haematobium: development of novel microsatellite markers and their application to schistosomiasis control in Mali.Semantic proximity Read ↗

Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: the effect of sampling approach and parasite population definition.Semantic proximity Read ↗

Direct measurement of <i>in vitro</i> response to Praziquantel in <i>Schistosoma mansoni</i> populations from Western KenyaSemantic proximity Read ↗

Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populationsSemantic proximity Read ↗

New insights into the molecular epidemiology and population genetics of Schistosoma mansoni in Ugandan pre-school children and mothers.Semantic proximity Read ↗

Population genetic structure of Schistosoma mansoni and Schistosoma haematobium from across six sub-Saharan African countries: implications for epidemiology, evolution and control.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.