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Article

Detection of EGFR mutations by TaqMan mutation detection assays powered by competitive allele-specific TaqMan PCR technology.

BioMed research international - 1 Jan 2013

Roma Cristin, Esposito Claudia, Rachiglio Anna Maria, Pasquale Raffaella, Iannaccone Alessia, Chicchinelli Nicoletta, Franco Renato, Mancini Rita, Pisconti Salvatore, De Luca Antonella, Botti Gerardo, Morabito Alessandro, Normanno Nicola

Abstract excerpt

Epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC) are predictive of response to treatment with tyrosine kinase inhibitors. Competitive Allele-Specific TaqMan PCR (castPCR) is a highly sensitive and specific technology. EGFR mutations were assessed by TaqMan Mutation Detection Assays (TMDA) based on castPCR technology in 64 tumor samples: a training set of 30 NSCLC and 6...

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Identifiers

PMID: 24364033
DOI: 10.1155/2013/385087
PMCID: PMC3864078

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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