Article
Mutation detection by real-time PCR: a simple, robust and highly selective method.
PloS one - 1 Jan 2009
Morlan John, Baker Joffre, Sinicropi Dominick
Abstract excerpt
BACKGROUND: Molecular tests for diagnosis of disease, particularly cancer, are gaining increased acceptance by physicians and their patients for disease prognosis and selection of treatment options. Gene expression profiles and genetic mutations are key parameters used for the molecular characterization of tumors. A variety of methods exist for mutation analysis but the development of assays with high selectivity...
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