Article
M2-polarized tumor-associated macrophages are associated with poor prognoses resulting from accelerated lymphangiogenesis in lung adenocarcinoma.
Clinics (Sao Paulo, Brazil) - 1 Jan 2011
Zhang Bicheng, Yao Guoqing, Zhang Yafei, Gao Juan, Yang Bo, Rao Zhiguo, Gao Jianfei
Abstract excerpt
OBJECTIVES: Tumor-associated macrophages have been implicated in promoting tumor growth, progression and metastasis. However, the activated phenotype (M1 or M2) of tumor-associated macrophages remains unknown in solid tumors. Therefore, this study examined the density and prognostic significance of M2-polarized tumor-associated macrophages in lung adenocarcinoma. METHODS: Tumor specimens from 65 lung...
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