Article
Macrophage polarization at the crossroad between HIV-1 infection and cancer development.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2013
Alfano Massimo, Graziano Francesca, Genovese Luca, Poli Guido
Abstract excerpt
Mononuclear phagocytes play a fundamental role in the tissue homeostasis and innate defenses against viruses and other microbial pathogens. In addition, they are likely involved in several steps of cancer development. Circulating monocytes and tissue macrophages are target cells of viral infections, including human cytomegalovirus, human herpes virus 8, and the HIV, and alterations of their functional and...
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