Article

An extra-genital cell population contributes to urethra closure during mouse penis development

2023-11-11

Abstract excerpt

Hypospadias, or incomplete closure of the urethra along the penis, is the second most common birth defect in the United States. We discovered a population of extra- genital mesenchymal cells that are essential for proper penile urethra closure in mouse embryos. This extra-genital population first appeared in the mesenchyme posterior to the hindlimb of the fetus after the onset of penis formation. These extra-genit...

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Literature Corpus work: 53d6afd1-ad84-500a-af21-318acdd03add
DOI: 10.1101/2023.11.09.564741

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