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Article

Delineating a conserved genetic cassette promoting outgrowth of body appendages.

PLoS genetics - 1 Jan 2013

Lin Congxing, Yin Yan, Bell Sheila M, Veith G Michael, Chen Hong, Huh Sung-Ho, Ornitz David M, Ma Liang

Abstract excerpt

The acquisition of the external genitalia allowed mammals to cope with terrestrial-specific reproductive needs for internal fertilization, and thus it represents one of the most fundamental steps in evolution towards a life on land. How genitalia evolved remains obscure, and the key to understanding this process may lie in the developmental genetics that underpins the early establishment of the genital...

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PMID: 23358455
DOI: 10.1371/journal.pgen.1003231
PMCID: PMC3554569

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FGF8

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