Defining the molecular pathologies in cloaca malformation: similarities between mouse and human

Abstract excerpt

Anorectal malformations are congenital anomalies that form a spectrum of disorders, from the most benign type with excellent functional prognosis, to very complex, such as cloaca malformation in females in which the rectum, vagina and urethra fail to develop separately and instead drain via a single common channel into the perineum. The severity of this phenotype suggests that the defect occurs in the early...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Congenital gastrointestinal and neural anomalies
• Share to Hedgehog Signaling Pathway Studies
• Share to Urological Disorders and Treatments