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Article

Down-regulation of Na+-coupled glutamate transporter EAAT3 and EAAT4 by AMP-activated protein kinase.

Journal of neurochemistry - 1 Jun 2010

Sopjani Mentor, Alesutan Ioana, Dërmaku-Sopjani Miribane, Fraser Scott, Kemp Bruce E, Föller Michael, Lang Florian

Abstract excerpt

The glutamate transporters EAAT3 and EAAT4 are expressed in neurons. They contribute to the cellular uptake of glutamate and aspartate and thus to the clearance of the excitatory transmitters from the extracellular space. During ischemia, extracellular accumulation of glutamate may trigger excito...

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Source

Identifiers

PMID: 20218975
DOI: 10.1111/j.1471-4159.2010.06678.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20218975-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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