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Article

STAT3 gene mutations and their association with pure red cell aplasia in large granular lymphocyte leukemia.

Cancer science - 1 Mar 2014

Ishida Fumihiro, Matsuda Kazuyuki, Sekiguchi Nodoka, Makishima Hideki, Taira Chiaki, Momose Kayoko, Nishina Sayaka, Senoo Noriko, Sakai Hitoshi, Ito Toshiro, Kwong Yok-Lam

Abstract excerpt

Large granular lymphocyte leukemia (LGL L) has been morphologically characterized as a group of lymphoproliferative diseases that include T-cell large granular lymphocytic leukemia (T-LGL L) and chronic lymphoproliferative disorders of natural killer cells (CLPD-NK). We investigated mutations in the Src homology 2 (SH2) domain of the signal transducer and activator of transcription 3 (STAT3) gene in Asian cohorts...

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Share to Aged, 80 and over
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Association Studies

Share to Leukemia, Large Granular Lymphocytic

Share to Mutation, Missense

Share to STAT3 Transcription Factor

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Source

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Identifiers

PMID: 24350896
DOI: 10.1111/cas.12341
PMCID: PMC4317942

Genes

STAT3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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