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Article

Application of SNP microarrays to the genome-wide analysis of chromosomal instability in premalignant airway lesions.

Cancer prevention research (Philadelphia, Pa.) - 1 Feb 2014

Nakachi Ichiro, Rice Jessica L, Coldren Christopher D, Edwards Michael G, Stearman Robert S, Glidewell Steven C, Varella-Garcia Marileila, Franklin Wilbur A, Keith Robert L, Lewis Marina T, Gao Bifeng, Merrick Daniel T, Miller York E, Geraci Mark W

Abstract excerpt

Chromosomal instability is central to the process of carcinogenesis. The genome-wide detection of somatic chromosomal alterations (SCA) in small premalignant lesions remains challenging because sample heterogeneity dilutes the aberrant cell information. To overcome this hurdle, we focused on the B allele frequency data from single-nucleotide polymorphism microarrays (SNP arrays). The difference of allelic...

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Source

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Identifiers

PMID: 24346345
DOI: 10.1158/1940-6207.CAPR-12-0485
PMCID: PMC3926809

Genes

RASGRP3
RNF20
SSBP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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