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Article

Genome-wide allelic state analysis on flow-sorted tumor fractions provides an accurate measure of chromosomal aberrations.

Cancer research - 15 Dec 2008

Corver Willem E, Middeldorp Anneke, ter Haar Natalja T, Jordanova Ekaterina S, van Puijenbroek Marjo, van Eijk Ronald, Cornelisse Cees J, Fleuren Gert Jan, Morreau Hans, Oosting Jan, van Wezel Tom

Abstract excerpt

Chromosomal aberrations are a common characteristic of cancer and are associated with copy number abnormalities and loss of heterozygosity (LOH). Tumor heterogeneity, low tumor cell percentage, and lack of knowledge of the DNA content impair the identification of these alterations especially in a...

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Source

Identifiers

PMID: 19074902
DOI: 10.1158/0008-5472.CAN-08-2665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19074902-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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