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Analyzing cancer samples with SNP arrays.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Van Loo Peter, Nilsen Gro, Nordgard Silje H, Vollan Hans Kristian Moen, Børresen-Dale Anne-Lise, Kristensen Vessela N, Lingjærde Ole Christian

Abstract excerpt

Single nucleotide polymorphism (SNP) arrays are powerful tools to delineate genomic aberrations in cancer genomes. However, the analysis of these SNP array data of cancer samples is complicated by three phenomena: (a) aneuploidy: due to massive aberrations, the total DNA content of a cancer cell can differ significantly from its normal two copies; (b) nonaberrant cell admixture: samples from solid tumors do not...

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PMID: 22130873
DOI: 10.1007/978-1-61779-400-1_4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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