Article
Increasing genomic instability during premalignant neoplastic progression revealed through high resolution array-CGH.
Genes, chromosomes & cancer - 1 Jun 2007
Lai Lisa A, Paulson Thomas G, Li Xiaohong, Sanchez Carissa A, Maley Carlo, Odze Robert D, Reid Brian J, Rabinovitch Peter S
Abstract excerpt
Chromosomal instability is regarded as an underlying mechanism of neoplastic progression, integral to the clonal selection and evolution that leads to cancer. We evaluated chromosomal instability in premalignant Barrett's esophagus tissue using high resolution Affymetrix mapping 100K SNP arrays a...
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