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Article

p53 E3 ubiquitin protein ligase homolog regulates p53 in vivo in the adult mouse eye lens.

Molecular vision - 1 Jan 2013

Jaramillo-Rangel Gilberto, Ortega-Martínez Marta, Sepúlveda-Saavedra Julio, Saucedo-Cárdenas Odila, Montes-de-Oca-Luna Roberto

Abstract excerpt

PURPOSE: p53 is a transcription factor that plays an important role in preventing cancer development. p53 participates in relevant aspects of cell biology, including apoptosis and cell cycle control and must be strictly regulated to maintain normal tissue homeostasis. p53 E3 ubiquitin protein ligase homolog (Mdm2) is an important negative regulator of p53. The purpose of this study was to determine if Mdm2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24339722
PMCID: PMC3857160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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