Article
Post-transcriptional regulation of wnt8a is essential to zebrafish axis development.
Developmental biology - 1 Feb 2014
Wylie Annika D, Fleming Jo-Ann G W, Whitener Amy E, Lekven Arne C
Abstract excerpt
wnt8a Is essential for normal patterning during vertebrate embryonic development, and either gain or loss-of-function gene dysregulation results in severe axis malformations. The zebrafish wnt8a locus is structured such that transcripts may possess two regulatory 3' untranslated regions (UTRs), raising the possibility of post-transcriptional regulation as an important mode of wnt8a signaling control. To determine...
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