Article
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs.
Science (New York, N.Y.) - 7 Apr 2006
Giraldez Antonio J, Mishima Yuichiro, Rihel Jason, Grocock Russell J, Van Dongen Stijn, Inoue Kunio, Enright Anton J, Schier Alexander F
Abstract excerpt
MicroRNAs (miRNAs) comprise 1 to 3% of all vertebrate genes, but their in vivo functions and mechanisms of action remain largely unknown. Zebrafish miR-430 is expressed at the onset of zygotic transcription and regulates morphogenesis during early development. By using a microarray approach and i...
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