Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypomethylation of SNCA in blood of patients with sporadic Parkinson's disease.

Journal of the neurological sciences - 15 Feb 2014

Ai San-xi, Xu Qian, Hu Ya-cen, Song Cheng-yuan, Guo Ji-feng, Shen Lu, Wang Chun-rong, Yu Ri-li, Yan Xin-xiang, Tang Bei-sha

Abstract excerpt

SNCA is a pathogenic gene identified in rare familial PD, and over-expression of SNCA was suggested in the pathogenesis of familial and sporadic PD. Rep1 polymorphism of SNCA was associated with susceptibility to sporadic PD and SNCA expression in intro and in vivo. Hypomethylation in SNCA intron...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to alpha-Synuclein
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Introns

Share to Parkinson Disease

Share to Polymorphism, Genetic

Share to RNA, Messenger

Source

Identifiers

PMID: 24326201
DOI: 10.1016/j.jns.2013.11.033

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24326201-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypomethylation of SNCA in blood of patients with sporadic Parkinson's disease.PMID 24326201Read ↗

The rs3756063 polymorphism is associated with SNCA methylation in the Chinese Han population.Semantic proximity Read ↗

SNCA REP1 and Parkinson's disease.Semantic proximity Read ↗

Hypomethylation of intron1 of α-synuclein gene does not correlate with Parkinson’s diseaseSemantic proximity Read ↗

Genetic Regulation of α-Synuclein mRNA Expression in Various Human Brain TissuesSemantic proximity Read ↗

Epigenetic regulation in Parkinson's disease.Semantic proximity Read ↗

SNCA Gene Methylation in Parkinson’s Disease and Multiple System AtrophySemantic proximity Read ↗

Parkinson's disease correlates with promoter methylation in the α-synuclein gene.Semantic proximity Read ↗

Genetic association between alpha-synuclein and idiopathic Parkinson's disease.Semantic proximity Read ↗

Methylation regulates alpha-synuclein expression and is decreased in Parkinson's disease patients' brains.Semantic proximity Read ↗

Pyrosequencing analysis of SNCA methylation levels in leukocytes from Parkinson's disease patientsSemantic proximity Read ↗

CpG demethylation enhances alpha-synuclein expression and affects the pathogenesis of Parkinson's disease.Semantic proximity Read ↗

Variant in the 3' region of SNCA associated with Parkinson's disease and serum α-synuclein levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.