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Article

Whole genome sequencing reveals complex evolution patterns of multidrug-resistant Mycobacterium tuberculosis Beijing strains in patients.

PloS one - 1 Jan 2013

Merker Matthias, Kohl Thomas A, Roetzer Andreas, Truebe Leona, Richter Elvira, Rüsch-Gerdes Sabine, Fattorini Lanfranco, Oggioni Marco R, Cox Helen, Varaine Francis, Niemann Stefan

Abstract excerpt

Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains represent a major threat for tuberculosis (TB) control. Treatment of MDR-TB patients is long and less effective, resulting in a significant number of treatment failures. The development of further resistances leads to extensively drug-resistant (XDR) variants. However, data on the individual reasons for treatment failure, e.g. an induced...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Genome, Bacterial

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 24324807
DOI: 10.1371/journal.pone.0082551
PMCID: PMC3855793

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Source receipt: pubmed, retrieved 7 Sept 2026.

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