Article
Diversity and evolution of Mycobacterium tuberculosis: moving to whole-genome-based approaches.
Cold Spring Harbor perspectives in medicine - 4 Sept 2014
Niemann Stefan, Supply Philip
Abstract excerpt
Genotyping of clinical Mycobacterium tuberculosis complex (MTBC) strains has become a standard tool for epidemiological tracing and for the investigation of the local and global strain population structure. Of special importance is the analysis of the expansion of multidrug (MDR) and extensively drug-resistant (XDR) strains. Classical genotyping and, more recently, whole-genome sequencing have revealed that the...
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