Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of Serial Multidrug-Resistant Tuberculosis Strains Causing Treatment Failure and Within-Host Evolution by Whole-Genome Sequencing.

mSphere - 23 Dec 2020

Chen Xinchang, He Guiqing, Lin Siran, Wang Shiyong, Sun Feng, Chen Jiazhen, Zhang Wenhong

Abstract excerpt

The cure rate of multidrug-resistant tuberculosis (MDR-TB) is relatively low in China. The reasons for the treatment failure and within-host evolution during treatment have not been sufficiently studied. All MDR-TB patients receiving standard treatment from January 2014 to September 2016 at a designated TB Hospital in Zhejiang Province were retrospectively included and grouped according to their known treatment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amikacin
Share to Antitubercular Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

Share to Moxifloxacin

Share to Mycobacterium tuberculosis

Share to Treatment Failure

Share to Tuberculosis, Multidrug-Resistant

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 33361124
DOI: 10.1128/mSphere.00884-20
PMCID: PMC7763549

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of Serial Multidrug-Resistant Tuberculosis Strains Causing Treatment Failure and Within-Host Evolution by Whole-Genome Sequencing.PMID 33361124Read ↗

Whole-Genome Sequencing to Predict Mycobacterium tuberculosis Drug Resistance: A Retrospective Observational Study in Eastern ChinaSemantic proximity Read ↗

Whole-genome sequencing for analyzing the transmission characteristics of drug-resistant Mycobacterium tuberculosis in Ganzhou, China.Semantic proximity Read ↗

Whole-genome sequencing reveals transmission pattern and drug resistance of Mycobacterium tuberculosis intra- or inter-hosts.Semantic proximity Read ↗

Whole-Genome Sequencing Analysis of Serially Isolated Multi-Drug and Extensively Drug Resistant Mycobacterium tuberculosis from Thai Patients.Semantic proximity Read ↗

Evaluation of WHO catalog of mutations and five WGS analysis tools for drug resistance prediction of Mycobacterium tuberculosis isolates from China.Semantic proximity Read ↗

Whole genome sequencing of Mycobacterium tuberculosis for detection of drug resistance: a systematic review.Semantic proximity Read ↗

Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: progress, promise, and challengesSemantic proximity Read ↗

Whole-genome sequencing for surveillance of tuberculosis drug resistance and determination of resistance level in China.Semantic proximity Read ↗

Prediction of treatment outcomes for multidrug-resistant tuberculosis by whole-genome sequencing.Semantic proximity Read ↗

Whole-genome sequencing of Mycobacterium tuberculosis for prediction of drug resistance.Semantic proximity Read ↗

Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized careSemantic proximity Read ↗

Sequence-based detection of first-line and second-line drugs resistance-associated mutations in Mycobacterium tuberculosis isolates in Isfahan, Iran.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.