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Whole-Genome Sequencing Analysis of Serially Isolated Multi-Drug and Extensively Drug Resistant Mycobacterium tuberculosis from Thai Patients.

PloS one - 1 Jan 2016

Faksri Kiatichai, Tan Jun Hao, Disratthakit Areeya, Xia Eryu, Prammananan Therdsak, Suriyaphol Prapat, Khor Chiea Chuen, Teo Yik-Ying, Ong Rick Twee-Hee, Chaiprasert Angkana

Abstract excerpt

Multi-drug and extensively drug-resistant tuberculosis (MDR and XDR-TB) are problems that threaten public health worldwide. Only some genetic markers associated with drug-resistant TB are known. Whole-genome sequencing (WGS) is a promising tool for distinguishing between re-infection and persistent infection in isolates taken at different times from a single patient, but has not yet been applied in MDR and...

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Identifiers

PMID: 27518818
DOI: 10.1371/journal.pone.0160992
PMCID: PMC4982626

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Source receipt: pubmed, retrieved 7 Sept 2026.

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