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Article

Identification of natural splice variants of SAMHD1 in virus-infected HCC.

Oncology reports - 1 Feb 2014

Shi Yunpeng, Lv Guoyue, Chu Zhe, Piao Liling, Liu Xingkai, Wang Tuo, Jiang Yanfang, Zhang Ping

Abstract excerpt

It has been previously shown that the sterile alpha motif domain and HD domain-containing protein 1 (SAMHD1) can act as a retroviral restriction factor by inhibiting HIV‑1 infection, but whether it has any roles in cancer is still unclear. In the present study, we identified several SAMHD1 splice variants naturally occurring in liver cancer and investigated their roles in regulating drug susceptibility. SAMHD1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24317272
DOI: 10.3892/or.2013.2895

Genes

SAMHD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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