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Article

SAMHD1’s protein expression profile in humans

2 Feb 2015

Abstract excerpt

The deoxynucleoside triphosphate triphosphohydrolase and 3' → 5' exonuclease SAMHD1 restricts HIV-1 infection in noncycling hematopoietic cells in vitro, and SAMHD1 mutations are associated with AGS. Little is known about the in vivo expression and functional regulation of this cellular factor. Here, we first assessed the SAMHD1 protein expression profile on a microarray of 25 human tissues from >210 donors and...

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PMID: 25646359
DOI: 10.1189/jlb.4hi0714-338rr

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