Evidence for field effect cancerization in colorectal cancer

doi:10.1016/j.ygeno.2013.11.003

Article

Evidence for field effect cancerization in colorectal cancer

4 Dec 2013

Abstract excerpt

We compared transcript expression, and chromosomal changes on a series of tumors and surrounding tissues to determine if there is evidence of field cancerization in colorectal cancer. Epithelial cells were isolated from tumors and areas adjacent to the tumors ranging from 1 to 10cm. Tumor abnormalities mirrored those previously reported for colon cancer and while the number and size of the chromosomal...

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