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Article

Field Carcinogenesis in Cancer Evolution: What the Cell Is Going On?

6 Oct 2020

Abstract excerpt

Field carcinogenesis describes the prevalence of tumor-related alterations in normal appearing tissues. Here, we summarize recent efforts in profiling molecular field dynamics for resolving early events in cancer evolution. We also highlight gaps in our knowledge of the molecular and cellular heterogeneity of field carcinogenesis and propose directions to tackle these voids using single-cell-based approaches and...

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PMID: 33023945
DOI: 10.1158/0008-5472.can-20-1956

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