Combination of human leukocyte antigen and killer cell immunoglobulin-like receptor genetic background influences the onset age of hepatocellular carcinoma in male patients with hepatitis B virus infection.

doi:10.1155/2013/874514

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Article

Combination of human leukocyte antigen and killer cell immunoglobulin-like receptor genetic background influences the onset age of hepatocellular carcinoma in male patients with hepatitis B virus infection.

Clinical & developmental immunology - 1 Jan 2013

Pan Ning, Qiu Jie, Sun Hang, Miao Fengqin, Shi Qian, Xu Jinhuan, Jiang Wei, Jin Hui, Xie Wei, He Youji, Zhang Jianqiong

Abstract excerpt

To investigate whether killer cell immunoglobulin-like receptor (KIR) and human leukocyte antigen (HLA) genetic background could influence the onset age of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV) infection, one hundred and seventy-one males with HBV-related HCC were enrolled. The presence of 12 loci of KIR was detected individually. HLA-A, -B, and -C loci were genotyped with high...

Topics

Adult
Age of Onset
Alleles
Carcinoma, Hepatocellular
Genotype
HLA Antigens
Hepatitis B
Hepatitis B virus
Humans
Ligands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms

Male

Middle Aged

Polymorphism, Genetic

Receptors, KIR

Sex Factors

Source

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Identifiers

PMID: 24312130
DOI: 10.1155/2013/874514
PMCID: PMC3842051

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