Article
Association of KIR genotypes and haplotypes with susceptibility to chronic hepatitis B virus infection in Chinese Han population.
Cellular & molecular immunology - 1 Dec 2008
Lu Zhiming, Zhang Bingchang, Chen Shijun, Gai Zhongtao, Feng Zhaolei, Liu Xiangdong, Liu Yiqing, Wen Xin, Li Li, Jiao Yulian, Ma Chunyan, Shao Song, Cui Xiangfa, Chen Guojian, Li Jianfeng, Zhao Yueran
Abstract excerpt
Killer immunoglobulin-like receptor (KIR) genes can regulate the activation of NK and T cells upon interaction with HLA class I molecules. Hepatitis B virus (HBV) infection has been regarded as a multi-factorial disorder disease. Previous studies revealed that KIRs were involved in HCV and HIV infection or clearance. The aim of this study was to explore the possibility of the inheritance of KIR genotypes and...
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