Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Editing livestock genomes with site-specific nucleases.

Reproduction, fertility, and development - 1 Jan 2013

Carlson Daniel F, Tan Wenfang, Hackett Perry B, Fahrenkrug Scott C

Abstract excerpt

Over the past 5 years there has been a major transformation in our ability to precisely manipulate the genomes of animals. Efficiencies of introducing precise genetic alterations in large animal genomes have improved 100000-fold due to a succession of site-specific nucleases that introduce double-strand DNA breaks with a specificity of 10(-9). Herein we describe our applications of site-specific nucleases,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Targeting
Share to Animals, Genetically Modified
Share to Cellular Reprogramming

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Deoxyribonucleases

Share to Genetic Engineering

Share to Genome

Share to Ribonucleases

Share to Sus scrofa

Source

Identifiers

PMID: 24305179
DOI: 10.1071/RD13260

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Editing livestock genomes with site-specific nucleases.PMID 24305179Read ↗

Efficient nonmeiotic allele introgression in livestock using custom endonucleases.Semantic proximity Read ↗

Impact of CRISPR-Cas9-Based Genome Engineering in Farm AnimalsSemantic proximity Read ↗

Genome Engineering at the Dawn of the Golden AgeSemantic proximity Read ↗

Gene Editing and Gene Therapy: Entering Uncharted Territory in Veterinary OncologySemantic proximity Read ↗

Efficient Generation of Gene-Modified Pigs Harboring Precise Orthologous Human Mutation via CRISPR/Cas9-Induced Homology-Directed Repair in Zygotes.Semantic proximity Read ↗

Recent advances in genome editing and creation of genetically modified pigsSemantic proximity Read ↗

Programmable large DNA deletion, replacement, integration, and inversion with twin prime editing and site-specific recombinasesSemantic proximity Read ↗

Efficient generation of targeted and controlled mutational events in porcine cells using nuclease-directed homologous recombination.Semantic proximity Read ↗

Targeted gene therapies: tools, applications, optimization.Semantic proximity Read ↗

Genome Editing Strategies to Protect Livestock from Viral InfectionsSemantic proximity Read ↗

Efficient introgression of allelic variants by embryo-mediated editing of the bovine genome.Semantic proximity Read ↗

Live pigs produced from genome edited zygotes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.