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Article

Targeted gene therapies: tools, applications, optimization.

Critical reviews in biochemistry and molecular biology - 1 Jan 2000

Humbert Olivier, Davis Luther, Maizels Nancy

Abstract excerpt

Many devastating human diseases are caused by mutations in a single gene that prevent a somatic cell from carrying out its essential functions, or by genetic changes acquired as a result of infectious disease or in the course of cell transformation. Targeted gene therapies have emerged as potential strategies for treatment of such diseases. These therapies depend upon rare-cutting endonucleases to cleave at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22530743
DOI: 10.3109/10409238.2012.658112
PMCID: PMC3338207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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