Article
Dendritic cells derived from murine colonic mucosa have unique functional and phenotypic characteristics.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2007
Takenaka Shunsuke, Safroneeva Ekaterina, Xing Zhou, Gauldie Jack
Abstract excerpt
Dendritic cells (DCs) residing in different tissues and exposed to different organisms are likely to have different reactivities to their surrounding environment. Many studies use in vitro generated DCs to examine functions of these cells, but such cells may not truly reflect the nature of DCs and their in situ activities in vivo. We have used magnetic label-based technique to isolate colonic DCs to conduct...
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