Article
Study of TLR4 and IL-8 gene polymorphisms in H.pylori-induced inflammation in gastric cancer in an ethnic Kashmiri population.
Immunological investigations - 1 Jan 2014
Qadri Qurteeba, Rasool Roohi, Afroze Dil, Naqash Sameer, Gulzar G M, Yousuf Adfar, Siddiqi M A, Shah Zafar A
Abstract excerpt
BACKGROUND: TLRs play an essential role in the initial handling of H. pylori and determine the clinical outcomes that range from simple asymptomatic gastritis to peptic ulcer disease and gastric cancer. Asp299Gly and Thr399Ile polymorphisms in TLR4 have been associated with a variety of inflammat...
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