Article
IL-1ß (+3953 C/T) and IL-8 (-251 A/T) Gene Polymorphisms in H. Pylori mediated Gastric Disorders
Iranian journal of immunology : IJI - 1 Jun 2010
Farshad Shohreh, Rasouli Manoochehr, Jamshidzadeh Akram, Hosseinkhani Ayda, Japoni Aziz, Alborzi Abdolvahab, Taghavi Alireza, Kazemi Asl Hossein, Ranjbar Reza
Abstract excerpt
BACKGROUND: Previous studies imply that IL-1 and IL-8 gene variations may play a crucial role in the genetic predisposition to different gastric disorders upon H. pylori infection. OBJECTIVE: The aim of this study was to determine the potential association between the prevalence of certain polymorphic sites and the risk of gastric disorders in Iranian population. METHODS: One hundred and forty three unrelated...
Topics
- DNA Mutational Analysis
- Gastritis
- Gene Frequency
- Genetic Association Studies
- Genetic Predisposition to Disease
- Haplotypes
- Helicobacter Infections
- Helicobacter pylori
- Humans
- Interleukin-1beta
- Interleukin-8
- Polymorphism, Genetic
- Stomach Ulcer