Article
Pharmacogenetics of G-protein-coupled receptors variants: FSH receptor and infertility treatment.
Best practice & research. Clinical endocrinology & metabolism - 1 Apr 2018
Santi Daniele, Potì Francesco, Simoni Manuela, Casarini Livio
Abstract excerpt
Infertility treatment may represent a paradigmatic example of precision medicine. Follicle-stimulating hormone (FSH) has been proposed as a valuable therapeutic option both in males and in females, even if a standardized approach is far to be established. To date, several genetic mutations as well as polymorphisms have been demonstrated to significantly affect the pathophysiology of FSH-FSH receptor (FSHR)...
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