Article
Genetic complexity of FSH receptor function.
Trends in endocrinology and metabolism: TEM - 1 Oct 2005
Gromoll Jörg, Simoni Manuela
Abstract excerpt
The interaction between follicle-stimulating hormone (FSH) and the FSH receptor (FSHR) is essential for normal oogenesis and spermatogenesis. Recently, single-nucleotide polymorphisms (SNPs) have been assigned to the FSHR gene. These give rise to different FSHR haplotypes that modify the action of FSH. In women, FSH sensitivities during the menstrual cycle and different cycle lengths are observed, depending on...
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