Reproductive physiology in young men is cumulatively affected by FSH-action modulating genetic variants: FSHR -29G/A and c.2039 A/G, FSHB -211G/T.

doi:10.1371/journal.pone.0094244

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Reproductive physiology in young men is cumulatively affected by FSH-action modulating genetic variants: FSHR -29G/A and c.2039 A/G, FSHB -211G/T.

PloS one - 1 Jan 2014

Grigorova Marina, Punab Margus, Punab Anna Maria, Poolamets Olev, Vihljajev Vladimir, Zilaitienė Birutė, Erenpreiss Juris, Matulevičius Valentinas, Laan Maris

Abstract excerpt

Follicle-Stimulating Hormone Receptor (FSHR) -29G/A polymorphism (rs1394205) was reported to modulate gene expression and reproductive parameters in women, but data in men is limited. We aimed to bring evidence to the effect of FSHR -29G/A variants in men. In Baltic young male cohort (n = 982; Estonians, Latvians, Lithuanians; aged 20.2 ± 2.0 years), the FSHR -29 A-allele was significantly associated with higher...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follicle Stimulating Hormone, beta Subunit

Share to Inhibins

Share to Oligospermia

Share to Organ Size

Share to Receptors, FSH

Share to Testis

Share to Testosterone

Source

Open in PubMed Open full text

Identifiers

PMID: 24718625
DOI: 10.1371/journal.pone.0094244
PMCID: PMC3981791

Genes

FSHR
FSHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reproductive physiology in young men is cumulatively affected by FSH-action modulating genetic variants: FSHR -29G/A and c.2039 A/G, FSHB -211G/T.PMID 24718625Read ↗

Mechanisms in endocrinology: Genetics of FSH action: a 2014-and-beyond view.Semantic proximity Read ↗

FSHB -211 G>T is a major genetic modulator of reproductive physiology and health in childbearing age women.Semantic proximity Read ↗

FSHB and FSHR gene variants exert mild modulatory effect on reproductive hormone levels and testis size but not on semen quality: A study of 2020 men from the general Danish population.Semantic proximity Read ↗

Genetically determined dosage of follicle-stimulating hormone (FSH) affects male reproductive parameters.Semantic proximity Read ↗

The -29G/A FSH receptor gene polymorphism is associated with higher FSH and LH levels in normozoospermic men.Semantic proximity Read ↗

The combination of genetic variants of the FSHB and FSHR genes affects serum FSH in women of reproductive age.Semantic proximity Read ↗

Combined effects of the variants FSHB -211G>T and FSHR 2039A>G on male reproductive parameters.Semantic proximity Read ↗

Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls.Semantic proximity Read ↗

A genome-wide association study identifies FSHR rs2300441 associated with follicle-stimulating hormone levels.Semantic proximity Read ↗

Association between follicle-stimulating hormone receptor polymorphisms and reproductive parameters in young men from the general population.Semantic proximity Read ↗

Pharmacogenetics of FSH Action in the MaleSemantic proximity Read ↗

Pharmacogenetics of FSH Action in the FemaleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.