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Article

Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome.

Obesity facts - 1 Jan 2009

Singmann Paula, Baumert Jens, Herder Christian, Meisinger Christa, Holzapfel Christina, Klopp Norman, Wichmann H-Erich, Klingenspor Martin, Rathmann Wolfgang, Illig Thomas, Grallert Harald

Abstract excerpt

OBJECTIVE: The metabolic syndrome, a major cluster of risk factors for cardiovascular diseases, shows increasing prevalence worldwide. Several studies have established associations of both apolipoprotein A5 (APOA5) gene variants and upstream stimulatory factor 1 (USF1) gene variants with blood lipid levels and metabolic syndrome. USF1 is a transcription factor for APOA5. METHODS: We investigated a possible...

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Source

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Identifiers

PMID: 20054229
DOI: 10.1159/000227288
PMCID: PMC2919429

Genes

APOA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome.PMID 20054229Read ↗

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